Lesson 1 Build a Better World
Two Heroes Who Fought a Deadly Disease
One evening in ____ November 1932, a bitterly cold wind blows fiercely as two figures emerge from a laboratory.
Darkness begins to fall as they set out into a world of ____ banks, collapsed industry, and widespread despair—a world ruined by three years of the Great Depression.
The ____ has come to an end, but for Pearl Kendrick and Grace Eldering, a different kind of work is about to begin.
They are on their way to visit the homes of children suffering from a deadly ____ called pertussis.
The two women go from home to home collecting samples from the sick children by the faint light of their ____.
They listen to the tragic stories of desperate and ____ parents as the children, coughing uncontrollably and struggling to breathe, barely hold on to life.
Pertussis is a bacterial disease characterized by serious coughing, breathing difficulties, and the high-pitched “whooping” sound that ____ with the disease make as they try to breathe in.
Because of this distinct sound, people ____ to call the disease “whooping cough.”
For a long time, this terrible illness was one of the greatest terrors of families with young children, because babies who contracted it had a ____ chance of dying.
In the 1930s, an average of 6,000 people died of whooping cough in the United States ____ year.
____ percent of them were children under five years of age.
The cause of the disease had been ____ in 1906, but the vaccines that had been developed were ineffective.
Scientists and researchers worked for more than 20 years to ____ an effective one, but their efforts were fruitless — until Kendrick and Eldering came along.
Pearl Kendrick studied bacteriology
Pearl Kendrick studied ____ in university and was recruited by the Michigan Department of Health in 1920.
It was there that she met fellow ____ Grace Eldering.
The two quickly bonded, and in 1932 they started working together on a vaccine for ____ cough.
Personal experience served as motivation for both of them, as they had ____ survived whooping cough as children themselves and remembered the severe pain of the disease.
Both scientists were ____ eager to promote children’s health.
Unfortunately, ____ funding was extremely limited due to the Great Depression.
Also, Kendrick and ____ had to develop the vaccine as a side project.
It was like having a second job for ____ they never received any payment.
Still, when they finished their normal duties each day, they would get started on the work that they were ____ about.
The ____ they faced did not stop them from persisting toward their goal.
They did not do the ____ to make extra money; instead, they worked to relieve the suffering of innocent children and their families.
They began the ____ of developing their vaccine by gathering samples of the bacteria that cause whooping cough.
To support them, local doctors and nurses provided “cough plates” from their ____.
The patients coughed onto a ____ dish, which was then put into an incubator.
This allowed the bacteria to grow into ____ that Kendrick and Eldering could analyze.
When they collected samples on their ____, they would go to the homes of sick children.
Each time, they were ____ once again of the dreadful suffering caused by the disease.
The sight of these innocent young victims coughing and ____ to breathe was a powerful reminder of the urgent need for an effective vaccine.
Kendrick and Eldering spent many long nights
Kendrick and Eldering spent many long nights studying the bacteria and finally produced a potential ____.
Before they performed any clinical trials, though, they ____ to be certain that it would not have any negative side effects on the subjects.
They ran many laboratory ____, and they even injected it into themselves to confirm that it was safe.
From 1934 to ____, they conducted their first field test with 1,592 children.
In the group of 712 vaccinated children, only four developed whooping cough, and none of these ____ were serious.
Despite the apparent success of the ____, Kendrick and Eldering wanted further confirmation of its effectiveness.
They became determined to expand their research and run more tests with ____ groups of children.
However, they were unable to proceed because they were ____ a severe lack of funds.
With thousands of children continuing to suffer from the ____, they found themselves in a desperate situation.
Luckily, they got ____ from an unexpected figure.
In 1936, ____ Lady Eleanor Roosevelt herself visited the laboratory and saw with her own eyes the efforts that Kendrick and Eldering were making in their battle against whooping cough.
____ Roosevelt, whose husband suffered from polio, was interested in fighting infectious diseases.
She spent ____ with the women and came to realize the enormous importance of their work.
With her help, Kendrick and Eldering were able to ____ enough funding to conduct a large-scale trial.
By 1937
By 1937, Kendrick and Eldering were able to include more than 4,200 ____ in their trial.
Just as in their first field test, the ____ group demonstrated a high level of immunity against the disease.
The scientific community was amazed at the results, and, in 1940, the vaccine started being distributed all across the ____ States.
Four years ____, it was added to the American Medical Association’s list of recommended immunizations, and soon after, there was a dramatic decline in whooping cough infections.
In the mid-1970s, the number of annual deaths caused by ____ cough, which had reached 7,518 in 1934, dropped to under 10.
Kendrick and Eldering were often told that they could have become very wealthy if they ____ patented their vaccine.
However, they replied that it ____ not been created by them alone, but with the help of many others.
They also avoided personal interviews, ____ wanting to reveal the great contribution they had made.
They said that they had genuinely enjoyed the challenge of ____ the vaccine, so the excessive praise that they received made them uncomfortable.
In the end, knowing that so many lives were being saved thanks to their hard ____ was enough of a reward for these remarkable and modest heroes.